Wine & Painkillers

[winecollector]

I'm curious to see how the rest of you feel about this, but when I have a headache at all I refrain from taking even the mildest of pain killers if I know I'm planning to drink wine later that day. Asprin, acetominiphin, ibuprophen, etc. I'm not sure if I'm being overly cautious, or if I'm being a fanatic. I've long been worried that it's too difficult on the liver to try and handle processing both alcohol & pain killers at the same time... but yet I know people who take this stuff regularly and think nothing of drinking while doing it. Any thoughts?